DARZALEX® Treatment:

DARZALEX® in combination with Velcade®
(bortezomib) + dexamethasone

The frequency and length of DARZALEX® infusions decreases over time.

On average, the first DARZALEX® infusion may take about seven hours. Future infusions will take less time, and last three to five hours, not including check-in and check-out time. After the initial rounds, DARZALEX® treatments are needed only once every four weeks.

Other medicines in this regimen are given as follows:

  • Velcade® (bortezomib) by injection or IV infusion on days 1, 4, 8, and 11 of each 21-day cycle for a total of 8 cycles*
  • dexamethasone by mouth once daily on days 1, 2, 4, 5, 8, 9, 11, and 12 for a total of eight 21-day cycles
    • On DARZALEX® infusion days, dexamethasone may be given as a pre-infusion medication and continued as a pre-medication after Vd discontinuation

*Please refer to the bortezomib Prescribing Information for more detailed information about twice-weekly bortezomib dosing.

Your dexamethasone dosing may be modified by your doctor. Please see the DARZALEX® Prescribing Information for more information.