DARZALEX® Treatment:

DARZALEX®in combination with Velcade®
(bortezomib) + thalidomide + dexamethasone

The frequency and length of DARZALEX® infusions decreases over time.

On average, the first DARZALEX® infusion may take about 7 hours. However, your doctor may choose to give the first dose as two shorter infusions over two consecutive days.

Future infusions will take less time and last 3 to 5 hours, not including check-in and check-out time. After the initial rounds, DARZALEX® treatments are needed only once every four weeks.

Other medicines in this regimen are given as follows:

  • Velcade (bortezomib) by injection or intravenously on Days 1, 4, 8, and 11 of each cycle
  • thalidomide by mouth every day during each cycle
  • dexamethasone by mouth or intravenously for Cycle 1-2 on Days 1, 2, 8, 9, 15, 16, 22, and 23; Cycle 3-4 on Days 1, 2, 8, 9, 15 and 16; and Cycle 5-6 on Days 1, 2, 8, 9, 15, and 16