What Are the Possible Side Effects of Treatment with DARZALEX®?
The most common side effects of DARZALEX® include tiredness, nausea, diarrhea, constipation, vomiting, muscle spasms, joint pain, back pain, fever, chills, dizziness, insomnia, cough, shortness of breath, swollen hands, ankles or feet, nerve damage causing tingling, numbness or pain, cold-like symptoms (upper respiratory infection).
Infusion reactions are common with DARZALEX® and can be severe. About half of people treated with DARZALEX® experienced an infusion reaction. These reactions are most likely to happen during the first infusion and are less likely to happen with future infusions.
If you do have an infusion reaction, your healthcare professional may temporarily stop your infusion or completely stop treatment with DARZALEX®.
Infusion reaction symptoms may include:
- shortness of breath or trouble breathing
- dizziness or lightheadedness (hypotension)
- throat tightness
- runny or stuffy nose
A healthcare professional will monitor you during your DARZALEX® infusion.
Changes in Blood Tests
DARZALEX® can affect blood test results used to match your blood for transfusions. These changes can last for up to 6 months after your final dose of DARZALEX®. Your healthcare professional will do blood tests to match your blood type before you start treatment with DARZALEX®. Tell all of your healthcare professionals that you are being treated with DARZALEX® before receiving blood transfusions.
Decreases in Blood Cell Counts
DARZALEX® can decrease white blood cell counts, which help fight infections, and blood cells called platelets, which help to clot blood. Tell your healthcare professionals if you develop fever or have signs of bruising or bleeding.
Tell your healthcare professional if you have any side effect that bothers your or that does not go away.