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Side Effects | DARZALEX® IV (daratumumab)

DARZALEX® side effects

Side effects

A side effect is an unwanted or unexpected reaction to a drug. Tell a member of your healthcare team if you have any side effect that bothers you or that does not go away.

The most common side effects of DARZALEX® include tiredness, nausea, diarrhea, constipation, vomiting, muscle spasms, joint pain, back pain, fever, chills, dizziness, trouble sleeping, cough, shortness of breath, swollen hands, ankles or feet, nerve damage causing tingling, numbness or pain, and cold-like symptoms (upper respiratory infection).

Infusion Reactions

Infusion reactions are common with DARZALEX® and can be severe. About half the people treated with DARZALEX® experience an infusion reaction. This is most likely to happen during the first infusion and less likely with future infusions. A healthcare professional will monitor you during every DARZALEX® infusion.

If you do have an infusion reaction, your healthcare professional may temporarily stop your infusion or completely stop treatment with DARZALEX®.

Infusion reaction symptoms may include:

  • shortness of breath or trouble breathing
  • dizziness or lightheadedness (hypotension)
  • cough
  • wheezing
  • throat tightness
  • runny or stuffy nose
  • headache
  • itching
  • nausea
  • vomiting
  • chills
  • fever

Questions to ask before and after treatment

Here are a few things you may want to ask your doctor so you can be better prepared for treatment with DARZALEX®:

  • What side effects should I watch for?
  • Do I need to make any changes to my diet during or after treatment?
  • What kind of exercise can or should I do while being treated?
  • What type of follow-up will I need after treatment and when?
  • How will we know if the cancer has come back? What should I watch for?

Generate your own list of questions with our Personalized Doctor Conversation Starter