Caregiver Stories: Harry’s Story

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NEWS ABOUT DARZALEX®

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A new option for patients with multiple myeloma: DARZALEX® can now be used in combination with Revlimid® (lenalidomide) and dexamethasone or Velcade® (bortezomib) and dexamethasone in patients who have received at least one prior medicine.

How does DARZALEX® work?
  • DARZALEX® is not chemotherapy. DARZALEX® is a monoclonal antibody that works with your immune system. Monoclonal antibodies work by attaching themselves to multiple myeloma cells in your body and directly killing them, and/or signaling your immune system to destroy them
  • DARZALEX® finds and attaches to a protein called CD38, which is present on the surface of cells, including high numbers on myeloma cells
RESULTS SEEN IN CLINICAL TRIALS
  • The main goal of the study was to measure the length of time patients live without their multiple myeloma getting worse or their passing away from any cause
    • Another goal was to measure response rate, which is the percentage of patients who responded to treatment. Talk to your doctor about how response is measured
  • The majority of patients responded to the following DARZALEX® combination treatments:
    • ​DARZALEX® was studied in combination with Revlimid® and dexamethasone (Rd) vs Rd alone in 569 patients who had received a minimum of 1 prior treatment
      • 9 out of 10 patients responded to DARZALEX® + Rd vs 7 out of 10 with Rd alone
    • DARZALEX® was studied in combination with Velcade® and dexamethasone (Vd) vs Vd alone in 498 patients who had received a minimum of 1 prior treatment
      • Almost 8 out of 10 patients responded to DARZALEX® + Vd vs almost 6 out of 10 with Vd alone
  • DARZALEX® combination treatments reduced patients’ risk of their disease getting worse or their passing away from any cause by more than 60%

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Revlimid® is a registered trademark of Celgene Corporation.
Velcade® is a registered trademark of Millennium Pharmaceuticals, Inc.

Harry | Caregiver

Caregiver since 2009

Caregiver Harry Caring for Someone with Multiple Myeloma Story

Debby and I have been together for quite a while—we were high-school sweethearts—so when she was diagnosed with multiple myeloma, I made it my mission to understand it. In the beginning, I found it incredibly difficult to watch her come to terms with her initial prognosis. Around that time, it seemed like she started giving up; at one point, she started to pick out my next wife, and that devastated me.

She has now come to terms with her diagnosis, and together we have taken on the challenge of navigating the multiple myeloma course.

I like to think of myself as her caddie. Instead of golf clubs, I carry her belongings, samples, and notes to different doctors. I’m not coaching her, but like a caddie, I’m there to keep Debby’s head focused. I take notes, observe, and give guidance when asked. I’ve also taken university courses in nursing and clinical trials because I want to know about and need to understand Debby’s disease to the fullest.

Looking back on the years, I have 2 pieces of advice for other caregivers, or “cancer caddies”:

  1. Educate yourself in a broader way—you have to learn the course, and the course will change, and sometimes you won’t play the same course every week—and if you have questions, ask your healthcare professional.
  2. Stay by your loved one’s side—especially when going to the doctor—and offer to take notes!

Read Debby’s story about living with multiple myeloma.