Living With Multiple Myeloma




More Possibilities

A new option for patients with multiple myeloma: DARZALEX® can now be used in combination with Revlimid® (lenalidomide) and dexamethasone or Velcade® (bortezomib) and dexamethasone in patients who have received at least one prior medicine.

How does DARZALEX® work?
  • DARZALEX® is not chemotherapy. DARZALEX® is a monoclonal antibody that works with your immune system. Monoclonal antibodies work by attaching themselves to multiple myeloma cells in your body and directly killing them, and/or signaling your immune system to destroy them
  • DARZALEX® finds and attaches to a protein called CD38, which is present on the surface of cells, including high numbers on myeloma cells
  • The main goal of the study was to measure the length of time patients live without their multiple myeloma getting worse or their passing away from any cause
    • Another goal was to measure response rate, which is the percentage of patients who responded to treatment. Talk to your doctor about how response is measured
  • The majority of patients responded to the following DARZALEX® combination treatments:
    • ​DARZALEX® was studied in combination with Revlimid® and dexamethasone (Rd) vs Rd alone in 569 patients who had received a minimum of 1 prior treatment
      • 9 out of 10 patients responded to DARZALEX® + Rd vs 7 out of 10 with Rd alone
    • DARZALEX® was studied in combination with Velcade® and dexamethasone (Vd) vs Vd alone in 498 patients who had received a minimum of 1 prior treatment
      • Almost 8 out of 10 patients responded to DARZALEX® + Vd vs almost 6 out of 10 with Vd alone
  • DARZALEX® combination treatments reduced patients’ risk of their disease getting worse or their passing away from any cause by more than 60%

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Revlimid® is a registered trademark of Celgene Corporation.
Velcade® is a registered trademark of Millennium Pharmaceuticals, Inc.

Emotional and Physical Coping

Living with multiple myeloma is a difficult journey. Your multiple myeloma may not respond to treatment or may come back after treatment. People living with multiple myeloma often have to cope with the emotional impact as well as physical issues such as fatigue and bone pain. That is why it’s important that you take care of yourself. Finding good resources for support and learning what you can about multiple myeloma may help you take a more active role and make informed decisions about your treatment and your disease.


Emotional Coping

How You Are Feeling Matters

Depending on where you are in your treatment journey, you may have different feelings about your multiple myeloma. Your feelings may change over time. You may feel anxious, afraid, uncertain, angry, or depressed. It is normal to have some or all of these feelings. Each person will handle them in a different way.

There are many things that may help you cope with your emotions:
  • Talk about your feelings. It’s OK to experience them
  • Ask for support from family, friends, and others. Having someone who will listen can be very helpful
  • Seek help through counseling and support groups
  • Find other ways to express your feelings, such as music, painting, or writing
  • Try deep breathing, meditation, and other relaxation exercises
  • Pay attention to your physical needs for rest and nutrition

Physical Coping

The Importance of Nutrition

Getting proper nutrition through a well-balanced diet is very important for people living with multiple myeloma. A nutritious diet of fresh fruits, vegetables, whole grains, and lean proteins, such as fish, poultry, or beans, is recommended. Try to limit your use of cream-based sauces, dressings, and dips, and try to avoid refined carbohydrates, such as pastries and sweetened breakfast cerals.

Be sure to talk to your healthcare provider before making any dietary changes.

Being Active Is Important

Exercising regularly can help reduce stress and relieve fatigue. Talk to your doctor before you start a new exercise program. Set goals to slowly increase your activity level. You may want to take a walk, do yoga, or try range-of-motion exercises to help reduce tiredness, relieve stress, and improve your sense of well-being.


Caregiver Information

As a caregiver, you play an important role during the treatment journey by providing encouragement and support.